Rotavirus B, non-structural protein 5 (IPR020244)

Short name: Rotavirus_B_NSP5

Family relationships



This entry represents non-structural protein 5 from rotaviruses. It is involved in genome replication, playing a crucial role in the formation of virus factories (viroplasms) which are large inclusions in the cytoplasm where core-like replication intermediates are assembled and RNA replication takes place. It forms a homodimer that interacts with VP1, VP2 and NSP2; these interaction lead to the formation of the virus factories.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.