ESAT-6-like protein EsxC (IPR020167)

Short name: ESAT-6-like_EsxC

Overlapping homologous superfamilies

Family relationships


Mycobacteria use various secretion pathways to allow protein transport across their impermeable cell envelope. One such pathway is termed T7S (also variously known as type VII-, ESAT-6- or ESX-secretion.) ESAT-6 stands for early secreted antigenic target 6 kDa protein; this was the first T7S-associated protein to be identified. ESAT-6 belongs to a family of small secreted proteins of approximately 100 amino acids, which share a helical structure and a characteristic hairpin bend. These proteins constitute the building blocks of the T7S system, and are named ESX proteins [PMID: 19876390].

This entry contains the ESAT-6-like protein EsxC.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.