Homologous Superfamily

Ribosomal protein L25/Gln-tRNA synthetase, N-terminal (IPR020056)

Short name: Rbsml_L25/Gln-tRNA_synth_N

Overlapping entries


The bacterial ribosomal protein L25 is bound to 5S rRNA along with L5 and L18, forming a separate domain of the ribosome [PMID: 10696113]. The solution structure of protein L25 uncomplexed with RNA shows two significantly disordered loops and a closed beta-barrel domain with a complex topology that has significant structural similarities to the N-terminal domain of the Thermus thermophilus ribosomal protein TL5, to the general stress protein CTC, and to the C-terminal anticodon-binding domain of Escherichia coli glutaminyl-tRNA synthetase (GlnRS) [PMID: 11418764, PMID: 12737824]. GlnRS contains a duplication consisting of two L25-like beta-barrels domains with the swapping of N-terminal strands.

This superfamily represents the N-terminal domain, which has a beta-barrel structure.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.