Domain

Motility protein FimV, N-terminal (IPR020012)

Short name: Motility_prot_FimV_N

Domain relationships

None.

Description

This region is found at, or about 200 amino acids from, the N terminus of FimV from Pseudomonas aeruginosa, TspA of Neisseria meningitidis, and related proteins [PMID: 10377136]. Disruption of FimV blocks twitching motility from type IV pili; which suggests a role for this family in peptidoglycan layer remodelling required by type IV fimbrial systems [PMID: 10846211]. Most but not all members of this protein family have a C-terminal region recognised by IPR020011. In between is a highly variable, often repeat-filled region rich in the negatively charged amino acids Asp and Glu.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs