Pyrimidine utilisation protein RutD (IPR019913)

Short name: Pyrimidine_utilisation_RutD

Overlapping homologous superfamilies

Family relationships



RutD is encoded within the Rut operon which allows growth on pyrimidines as sole nitrogen source [PMID: 16540542]. The function of this protein is not known, but it necessary for growth on pyrimidines, and cells lacking RutD produce much less of the Rut pathway intermediate malonic semialdehyde than normal [PMID: 20400551]. It is thought that RutD increases the rate of spontaneous hydrolysis of the toxic intermediate aminoacrylate to malonic semialdehyde.

GO terms

Biological Process

GO:0006212 uracil catabolic process

Molecular Function

GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.