Conserved Site

Malate synthase, conserved site (IPR019830)

Short name: Malate_synthase_CS


Malate synthase (EC: catalyses the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants. Malate synthase has a TIM beta/alpha-barrel fold [PMID: 10715138].

Malate synthase is a protein of 530 to 570 amino acids whose sequence is highly conserved across species [PMID: 2349836]. The signature pattern for this entry is to a very conserved region in the central section of the enzyme.

GO terms

Biological Process

GO:0006097 glyoxylate cycle

Molecular Function

GO:0004474 malate synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns