Binding Site

Germin, manganese binding site (IPR019780)

Short name: Germin_Mn-BS


Germins and germin-like proteins [PMID: 8143935] are a family of hexameric ubiquitous plant glycoproteins. They are not restricted to germinating grains as initially thought and therefore called 'germins', but they exist in all organs and developmental stages. They are all partly associated with the extracellular matrix.

A wide range of functions have been uncovered for germins and germin-like proteins: some act as oxalate oxidases (EC: or as superoxide dismutases (EC:, while others seem to be structural proteins or receptors for auxins or other proteins.

Germins and germin-like proteins are highly similar to slime mold spherulins 1a and 1b which are proteins that accumulate specifically during spherulation, a process induced by various forms of environmental stress which leads to encystment and dormancy.

The signature pattern for this entry is located in the central region and it contains three residues; 2 histidines and a glutamate, which are implicated in the binding of a manganese ion [PMID: 9541544].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0030145 manganese ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns