2-haloacid dehalogenase, DehI (IPR019714)

Short name: 2-haloacid_dehalogenase_DehI

Overlapping homologous superfamilies


Family relationships



Haloacid dehalogenases catalyse the removal of halides from organic haloacids. The 2-haloacid dehalogenase DehI can process both L- and D-substrates. A crucial aspartate residue is predicted to activate a water molecule for nucleophilic attack of the substrate chiral centre resulting in an inversion of the configuration of either L- or D-substrates in contrast to D-only enzymes [PMID: 18353360].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.