Family

Multidrug efflux pump accessory protein AcrZ (IPR019702)

Short name: AcrZ

Family relationships

None.

Description

AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. AcrZ binds to AcrB and is required for efflux of some, but not all substrates, suggesting it may influence the specificity of drug export [PMID: 23010927].

GO terms

Biological Process

GO:0006855 drug transmembrane transport

Molecular Function

GO:0015238 drug transmembrane transporter activity

Cellular Component

GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
HAMAP