Domain

Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding (IPR019581)

Short name: Prp8_U5-snRNA-bd

Domain relationships

None.

Description

The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [PMID: 16431982]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor [PMID: 16431982].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0030623 U5 snRNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam