Domain

Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain (IPR019564)

Short name: Sam37/metaxin_N

Domain relationships

None.

Description

Sam37 (also known as TOM37) is a component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex [PMID: 12891361]. It has homology with Metaxin-1, also part of the outer mitochondrial membrane beta-barrel protein transport complex [PMID: 17981999, PMID: 9045676].

GO terms

Biological Process

GO:0006626 protein targeting to mitochondrion

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005741 mitochondrial outer membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam