Domain

Galactokinase galactose-binding domain (IPR019539)

Short name: GalKase_gal-bd

Domain relationships

None.

Description

This entry represents a highly conserved galactokinase signature sequence which appears to be present in all galactokinases, irrespective of how many other ATP binding sites, etc that they carry [PMID: 10359639]. The function of this domain appears to be to bind galactose [PMID: 12796487], and it is normally located at the N terminus of these enzymes [PMID: 15526155]. It is associated with IPR013750 and IPR006204. While all enzymes in this entry posses galactokinase activity, some are annotated as N-acetylgalactosamine kinases as they also posses this enzyme activity.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam