Domain

Sorting nexin protein, WASP-binding domain (IPR019497)

Short name: Sorting_nexin_WASP-bd-dom

Overlapping homologous superfamilies

Domain relationships

Description

The C-terminal region of the Sorting nexin group of proteins appears to carry a BAR-like (Bin/amphiphysin/Rvs) domain. This domain is very diverse and the similarities with other BAR domains are few. In the Sorting nexins it is associated with IPR001683, and in combination with PX appears to be necessary to bind WASP along with p85 to form a multimeric signalling complex [PMID: 14993925].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam