Family

Chromatid cohesion factor MAU2 (IPR019440)

Short name: MAU2

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents the chromatid cohesion factor Mau2 and its homologues, including Scc4 from budding yeasts and Ssl3 from fission yeasts. Scc4 is a subunit of the cohesin loading factor complex (Scc2-Scc4), which is required for the loading of cohesin complexes onto chromosomes [PMID: 10882066]. Ssl3 is in complex with Mis4 (Scc2 homologue) and is required in G1 for cohesin binding to chromosomes [PMID: 16682348].

Animal Mau2 interacts with Nipbl (Scc2 orthologue), and both proteins are involved in sister chromatid cohesion and segregation [PMID: 19308700, PMID: 16802858, PMID: 16682347].

GO terms

Biological Process

GO:0007064 mitotic sister chromatid cohesion

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER