Family

Testis-specific protein TEX28/transmembrane and coiled-coil domains protein (IPR019394)

Short name: TEX28/TMCC

Family relationships

  • Testis-specific protein TEX28/transmembrane and coiled-coil domains protein (IPR019394)

Description

This entry includes testis-specific TEX28 and transmembrane and coiled-coil domains protein 1/2/3 (TMCC1/2/3). TMCC1 is an ER protein. Overexpression of TMCC1 or its transmembrane domains has been shown to cause defects in ER morphology [PMID: 24454821].

The Drosophila TMCC2 is an an amyloid protein precursor-interacting and apolipoprotein E-binding protein. It is required for normal development of the brain [PMID: 23409049].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam