Family

Mitoguardin (IPR019392)

Short name: Miga

Family relationships

None.

Description

Mitoguardin (Miga) was first identified in flies as a mitochondrial outer-membrane protein that promotes mitochondrial fusion. Later, the mammalian Miga homologues, Miga1 and Miga2, were identified. They are found to promote mitochondrial fusion by regulating mitochondrial phospholipid metabolism via MitoPLD [PMID: 26711011, PMID: 26716412].

GO terms

Biological Process

GO:0008053 mitochondrial fusion

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER