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Overview
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Pathways & interactions
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Structures
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Cross-references
Family
Lipoma HMGIC fusion partner-like protein (IPR019372)
Short name: LHFPL
Overlapping homologous superfamilies
None.
Family relationships
None.
Description
This is a group of proteins expressed from a series of genes referred to as Lipoma HMGIC fusion partner-like. The proteins carry four highly conserved transmembrane domains. In certain instances, as in LHFPL5, mutations cause deafness in humans [PMID: 16752389] or hypospadias [PMID: 16395596]. LHFPL1 is transcribed in six liver tumour cell lines [PMID: 15620218].