Family

Lipoma HMGIC fusion partner-like protein (IPR019372)

Short name: LHFPL

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This is a group of proteins expressed from a series of genes referred to as Lipoma HMGIC fusion partner-like. The proteins carry four highly conserved transmembrane domains. In certain instances, as in LHFPL5, mutations cause deafness in humans [PMID: 16752389] or hypospadias [PMID: 16395596]. LHFPL1 is transcribed in six liver tumour cell lines [PMID: 15620218].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER