Family

Clusterin-associated protein-1 (IPR019366)

Short name: Clusterin-associated_protein-1

Family relationships

None.

Description

This protein of 413 amino acids contains a central coiled-coil domain, possibly the region that binds to clusterin. Cluap1 expression is highest in the nucleus and gradually increases during late S to G2/M phases of the cell cycle and returns to the basal level in the G0/G1 phases. In addition, it is upregulated in colon cancer tissues compared to corresponding non-cancerous mucosa. It thus plays a crucial role in the life of the cell [PMID: 15480429].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER