Family

CCDC85 family (IPR019359)

Short name: CCDC85

Family relationships

None.

Description

This entry includes human CCDC85A/B/C and C. elegans Picc-1 protein. Picc-1 serves as a linker protein which helps to recruit the Rho GTPase-activating protein, pac-1, to adherens junctions [PMID: 25938815]. Human CCDC85B suppresses the beta-catenin activity in a p53-dependent manner [PMID: 17873903].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam