Family

Histone acetyltransferases subunit 3 (IPR019340)

Short name: Histone_AcTrfase_su3

Family relationships

None.

Description

This entry is found in Ada3 and homologous proteins which function as part of histone acetyltransferase complexes [PMID: 8413201]. Ada3 is an essential component of the Ada transcriptional coactivator (alteration/deficiency in activation) complex. It plays a key role in linking histone acetyltransferase-containing complexes to p53 (tumour suppressor protein) thereby regulating p53 acetylation, stability and transcriptional activation following DNA damage [PMID: 17272277].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam