Family

Conserved oligomeric Golgi complex subunit 7 (IPR019335)

Short name: COG7

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The conserved oligomeric Golgi (COG) complex is an eight-subunit (Cog1-8) peripheral Golgi protein involved in membrane trafficking and glycoconjugate synthesis [PMID: 16051600]. COG7 is required for normal Golgi morphology and trafficking. Defects in COG7 are the cause of congenital disorder of glycosylation type 2E (CDG2E). CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation [PMID: 15107842].

GO terms

Biological Process

GO:0006886 intracellular protein transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0017119 Golgi transport complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER