Family

BLOC-1-related complex subunit 6 (IPR019314)

Short name: BORCS6

Family relationships

None.

Description

BORC is a multisubunit complex that regulates the positioning of lysosomes at the cell periphery, and consequently affects cell migration. BORC associates with the lysosomal membrane, where it functions to recruit the small GTPase Arl8. This initiates a series of interactions that promote the microtubule-guided transport of lysosomes toward the cell periphery [PMID: 25898167, PMID: 25898163].

The BORC complex consists of 8 subunits. This family represents subunit 6.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam