Domain

Essential protein Yae1, N-terminal (IPR019191)

Short name: Essential_protein_Yae1_N

Domain relationships

None.

Description

This entry represents proteins found in the N-terminal region of the essential protein Yae1. Proteins containing this domain include ORAOV1 (Oral cancer-overexpressed protein 1) and YAE1 [PMID: 23318452]. Their function is not clear. In Saccharomyces cerevisiae, Lto1 (ORAOV1 homologue) forms a complex with Rli1 and Yae1, which relieves the toxic effects of reactive oxygen species (ROS) on biogenesis and function of the ribosome [PMID: 23318452].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam