Domain

CCDC93, coiled-coil domain (IPR019159)

Short name: CCDC93_CC

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the coiled-coil domain found in CCDC93.

Human CCDC93 is part of the COMMD/CCDC22/CCDC93 (CCC) complex that interacts with the multisubunit WASH complex, which is required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer [PMID: 25355947]. The CCC complex controls Notch activation by modulating its intracellular trafficking [PMID: 26553930].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam