Family

Nuclear protein DGCR14 (IPR019148)

Short name: Nuclear_protein_DGCR14

Family relationships

None.

Description

This entry represents a family of proteins of approximately 500 residues with alternating regions of low complexity and conservation where the domain similarities are strong. Apart from a predicted coiled-coil domain, no other known functional domains have been characterised. May be involved in pre-mRNA splicing and has been associated with the spliceosome C complex. The protein appears to be expressed in the nucleus, particularly in the pons sub-region of the brain. It is clearly necessary for normal development of the nervous system [PMID: 9499415].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER