Domain

Histone chaperone domain CHZ (IPR019098)

Short name: Histone_chaperone_domain_CHZ

Domain relationships

None.

Description

This domain is highly conserved from yeasts to humans and is part of the chaperone protein HIRIP3 in vertebrates which interacts with the H3.3 chaperone HIRA, implicated in histone replacement during transcription. N- and C- termini of Chz family members are relatively divergent but do contain similar acidic stretches rich in Glu/Asp residues, characteristic of all histone chaperones [PMID: 17289584].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART