Domain

Lamin-B receptor of TUDOR domain (IPR019023)

Short name: Lamin-B_rcpt_of_tudor

Domain relationships

None.

Description

The Lamin-B receptor is a chromatin and lamin binding protein in the inner nuclear membrane. It is one of the integral inner nuclear envelope membrane proteins responsible for targeting nuclear membranes to chromatin, being a downstream effector of Ran, a small Ras-like nuclear GTPase which regulates NE assembly. Lamin-B receptor interacts with importin beta, a Ran-binding protein, thereby directly contributing to the fusion of membrane vesicles and the formation of the nuclear envelope [PMID: 17251381].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam