Domain

Signal transduction histidine kinase RcsC, alpha-beta loop, C-terminal (IPR019017)

Short name: Sig_transdc_His_kin_a/b-loop_C

Domain relationships

None.

Description

This domain is found in the C terminus of the signal transduction response regulator (phospho-relay) kinase RcsC, between the ATP-binding region (IPR003594) and the receiver region (IPR001789). This domain forms a discrete alpha/beta/loop structure [PMID: 17005198]. The Rcs signalling pathway controls a variety of physiological functions like capsule synthesis, cell division or motility in prokaryotes. The Rcs regulation cascade, involving a multi-step phosphorelay between the two membrane-bound hybrid sensor kinases RcsC and RcsD and the global regulator RcsB, is, up to now, one of the most complicated regulatory systems in bacteria [PMID: 17005198].

GO terms

Biological Process

GO:0018106 peptidyl-histidine phosphorylation
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0005524 ATP binding
GO:0004673 protein histidine kinase activity
GO:0004871 signal transducer activity

Cellular Component

GO:0016021 integral component of membrane
GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PROSITE profiles