Family

Vacuolar ATPase assembly integral membrane protein Vma21 (IPR019013)

Short name: Vma21

Family relationships

None.

Description

The vacuolar ATPase assembly integral membrane protein VMA21 is required for the assembly of the integral membrane sector (V0 component) of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum [PMID: 15356264]. Mutations in the human VMA32 gene cause X-linked myopathy with excessive autophagy (XMEA), which is a childhood-onset disease characterised by progressive vacuolation and atrophy of skeletal muscle [PMID: 19379691].

GO terms

Biological Process

GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam
HAMAP