Domain

Fumarase C, C-terminal (IPR018951)

Short name: Fumarase_C_C

Domain relationships

None.

Description

Fumarase C catalyses the stereo-specific interconversion of fumarate to L-malate as part of the Krebs cycle. The full-length protein forms a tetramer with visible globular shape. FumaraseC_C is the C-terminal 65 residues referred to as domain 3. The core of the molecule consists of a bundle of 20 alpha-helices from the five-helix bundle of domain 2. The projections from the core of the tetramer are generated from domains 1 and 3 of each subunit [PMID: 8909293]. This entry does not appear to be part of either the active site or the activation site but is helical in structure forming a little bundle.

GO terms

Biological Process

GO:0006099 tricarboxylic acid cycle

Molecular Function

GO:0016829 lyase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam