Domain

Brefeldin A sensitivity protein-related, domain of unknown function DUF2421 (IPR018820)

Short name: BRE4-related_DUF2421

Domain relationships

None.

Description

This domain is found in several uncharacterised proteins and in Brefeldin A-sensitivity protein 4, which is a zinc finger protein containing five transmembrane domains. Brefeldin A-sensitivity protein 4 null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport [PMID: 9171100, PMID: 11378903, PMID: 11169758].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam