Muniscin C-terminal (IPR018808)

Short name: Muniscin_C

Overlapping homologous superfamilies


Domain relationships


The muniscins are a family of endocytic adaptors that is conserved from yeast to humans.This C-terminal domain is structurally similar to mu homology domains, and is the region of the muniscin proteins involved in the interactions with the endocytic adaptor-scaffold proteins Ede1-eps15. This interaction influences muniscin localisation. The muniscins provide a combined adaptor-membrane-tubulation activity that is important for regulating endocytosis [PMID: 19713939].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.