Putative stress-responsive protein (IPR018803)

Short name: Ish1/Msc1


This entry includes the stress response protein Ish1 from fission yeasts and meiotic sister chromatid recombination protein 1 (Msc1) from budding yeasts. This entry also includes some uncharacterised proteins from Acinetobacter baumannii.

Ish1 has a role in maintaining cell viability during stationary phase induced by stress response. It can be activated by the spc1 MAPK pathway [PMID: 11751918].

Msc1 was identified in a screen for mutants that show an increase in meiotic unequal sister-chromatid recombination (SCR) [PMID: 10511544]. Its function is not clear.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.