Family

FAM98 (IPR018797)

Short name: FAM98

Family relationships

None.

Description

FAM98A, B and C are glycine-rich proteins found from worms to humans. FAM98A contains a tubulin-binding calponin homology domain. It interacts with PLEKHM1 and functions in lysosome positioning in osteoclasts [PMID: 27777970]. FAM98A and FAM98B are included in a novel complex with DDX1 and C14orf166 and are involved in colorectal cancer progression [PMID: 28040436].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam