Family

Essential MCU regulator, mitochondrial (IPR018782)

Short name: MCU_reg

Family relationships

None.

Description

Essential MCU regulator (EMRE) is a component of the mitochondrial calcium uniporter complex in metazoa, a complex that mediates calcium uptake into mitochondria. It bridges the calcium-sensing components of the complex, MICU1 and MICU2, and the pore-forming subunit MCU, and it is essential for the complex uniporter activity [PMID: 24231807].

GO terms

Biological Process

GO:0051560 mitochondrial calcium ion homeostasis
GO:0036444 mitochondrial calcium uptake

Molecular Function

No terms assigned in this category.

Cellular Component

GO:1990246 uniplex complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam