tRNA-splicing endonuclease subunit Sen15 (IPR018593)

Short name: tRNA-endonuc_su_Sen15

Overlapping homologous superfamilies

Domain relationships



The Sen15 subunit of the tRNA intron-splicing endonuclease is one of the two structural subunits of this heterotetrameric enzyme. Residues 36-157 of this subunit possess a novel homodimeric fold. Each monomer consists of three alpha-helices and a mixed antiparallel/parallel beta-sheet. Two monomers of Sen15 fold with two monomers of Sen34, one of the two catalytic subunits, to form an alpha2-beta2 tetramer as part of the functional endonuclease assembly [PMID: 17166513].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.