Brinker DNA-binding domain (IPR018586)

Short name: Brinker_DNA-bd

Domain relationships



This DNA-binding domain is the first approx. 100 residues of the N-terminal end of Brinker. The structure of this domain in complex with DNA consists of four alpha-helices that contain a helix-turn-helix DNA recognition motif specific for GC-rich DNA. The Brinker nuclear repressor is a major element of the Drosophila Decapentaplegic morphogen signalling pathway [PMID: 16876822].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.