Domain

DNA replication checkpoint mediator, MRC1 domain (IPR018564)

Short name: Repl_chkpnt_MRC1_dom

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This putative domain is found in the most conserved region in mediator of replication checkpoint protein 1. This protein is a component of the replisome and is required for Rad3-dependent activation of the checkpoint kinase Cds1 in response to replication fork arrest [PMID: 14585996].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam