Frequency clock protein (IPR018554)

Short name: FRQ

Overlapping homologous superfamilies


Family relationships



Frequency (FRQ) is a key circadian clock component that is involved in the generation of biological rhythms in Neurospora crassa [PMID: 6455327]. It plays a role in rhythm stability, period length, and temperature compensation. FRQ behaves as a negative element in the circadian transcriptional loop [PMID: 19141472]. The protein has been shown to interact with itself via a coiled-coil [PMID: 11226160].

GO terms

Biological Process

GO:0007623 circadian rhythm
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005737 cytoplasm
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.