Binding Site

Rubredoxin, iron-binding site (IPR018527)

Short name: Rubredoxin_Fe_BS

Description

Rubredoxin is a low molecular weight iron-containing protein involved in electron transfer [PMID: 2244884, PMID: 1992166], sometimes replacing ferredoxin as an electron carrier [PMID: 7726577]. It is found in bacteria, archaea and plants.

The 3-D structures of a number of rubredoxins have been solved [PMID: 1303768, PMID: 3441010]. The fold belongs to the alpha+beta class, with 2 alpha-helices and 2-3 beta-strands. Its active site contains an iron ion which is co-ordinated by the sulphurs of four conserved cysteine residues forming an almost regular tetrahedron [PMID: 3441010]. The conserved cysteines reside on two loops, which are the most conserved regions of the protein. In addition, a ring of acidic residues in the proximity of the [Fe(Cys)4] centre is also well-conserved [PMID: 3441010].

This entry represents a conserved region which includes two of the cysteine residues that bind the iron atom.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0046872 metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns