Conserved Site

Carbohydrate kinase, FGGY, conserved site (IPR018483)

Short name: Carb_kinase_FGGY_CS

Description

FGGY carbohydrate kinases carry out ATP-dependent phosphorylation on one out of at least nine distinct sugar substrates [PMID: 22215998]. These enzymes include L-ribulokinase (EC:2.7.1.16) (gene araB); Erythriol kinase (EC:2.7.1.27) (gene eryA); L-fucolokinase (EC:2.7.1.51) (gene fucK); gluconokinase (EC:2.7.1.12) (gene gntK); glycerol kinase (EC:2.7.1.30) (gene glpK); xylulokinase (EC:2.7.1.17) (gene xylB); L-xylulose kinase (EC:2.7.1.53) (gene lyxK), D-ribulokinase (EC:2.7.1.47) (gene rbtK); and rhamnulokinase (EC:2.7.1.5) (gene rhaB). This family also contains a divergent subfamily functioning in quorum sensing, which phosphorylates AI-2, a bacterial signaling molecule derived from 4,5-dihydroxy-2,3-pentanedione (DPD) [PMID: 17274596].

This entry represents conserved regions found in the central and C-terminal regions of these enzymes.

GO terms

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0016773 phosphotransferase activity, alcohol group as acceptor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns