Bicaudal-D protein (IPR018477)

Short name: BICD

Overlapping homologous superfamilies


Family relationships



Bicaudal-D (BicD) is a family of motor adaptor proteins consist of three coiled-coiled domains. BicD plays an essential for the correct localization of maternal mRNAs in Drosophila's oocyte [PMID: 17827179] and functions as a regulator of the Golgi to ER retrograde transport in mammalian cells [PMID: 19018277]. BicD was suggested to be a linker bridging cargo and dynein and have roles in the regulation of cargo motility [PMID: 19754453]. It also functions as a novel regulator of neurotrophin (NT) signaling [PMID: 28215293].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008093 cytoskeletal adaptor activity
GO:0070840 dynein complex binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.