Domain

Centromere protein Cenp-F, N-terminal (IPR018463)

Short name: Centromere_CenpF_N

Domain relationships

None.

Description

Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore [PMID: 15939891]. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal part of the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein [PMID: 9704407].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam