Orange subgroup (IPR018352)

Short name: Orange_subgr

Domain relationships

  • Orange (IPR003650)
    • Orange subgroup (IPR018352)


This domain confers specificity among members of the Hairy/E(SPL) family. HES-2 (hairy and enhancer of split 2) is a transcription factor, and the hairy protein is a pair-rule protein that regulates embryonic segmentation and adult bristle patterning. These proteins are transcriptional repressors of genes that require the BHLH protein for their transcription.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.