Binding Site

Adrenodoxin, iron-sulphur binding site (IPR018298)

Short name: Adrenodoxin_Fe-S_BS


Adrenodoxin, putidaredoxin and terpredoxin are soluble 2Fe-2S iron-sulphur proteins that act as single electron carriers. They are a subgroup of the ferredoxin family of iron-sulphur proteins.

In mitochondrial monooxygenase systems, adrenodoxin transfers an electron from NADPH:adrenodoxin reductase to membrane-bound P450. In bacteria, putidaredoxin and terpredoxin serve as electron carriers between corresponding NADH-dependent ferredoxin reductases and soluble P450 [PMID: 2180940, PMID: 1629218]. The exact functions of other members of this family are not known.

In these proteins, four cysteine residues bind the iron-sulphur cluster. The patterns in this entry identifies three of these cysteines, which are involved in Fe-S binding.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0051537 2 iron, 2 sulfur cluster binding
GO:0009055 electron transfer activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns