Active Site

Glycoside hydrolase, family 11, active site (IPR018208)

Short name: Glyco_hydro_11_AS

Description

The microbial degradation of cellulose and xylans requires several types of enzymes such as endoglucanases (EC:3.2.1.4), cellobiohydrolases (EC:3.2.1.91) (exoglucanases), or xylanases (EC:3.2.1.8) [PMID: 2252383, PMID: 1886523]. Fungi and bacteria produces a spectrum of cellulolytic enzymes (cellulases) and xylanases which, on the basis of sequence similarities, can be classified into families. One of these families is known as the cellulase family G [PMID: 2806912] or as the glycosyl hydrolases family 11 [PMID: 1747104].

The two patterns in this entry are conserved regions in these enzymes and are centred on glutamic acid residues which have both been shown [PMID: 1359880], in Bacillus pumilis xylanase, to be necessary for catalytic activity.

GO terms

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns