Conserved Site

Wnt protein, conserved site (IPR018161)

Short name: Wnt_CS

Description

In humans, 19 Wnt proteins have been identified that share 27% to 83% amino-acid sequence identity and a conserved pattern of 23 or 24 cysteine residues [PMID: 11806834]. Wnt genes are highly conserved between vertebrate species sharing overall sequence identity and gene structure, and are slightly less conserved between vertebrates and invertebrates.

This entry represents the conserved site of the secreted growth factor Wnt.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns