Methylglyoxal synthase (MGS) [PMID: 10368300] catalyzes the conversion of
dihydroxyacetone phosphate to methylglyoxal and phosphate:
Glycerone phosphate = methylglyoxal + phosphate
bacteria with an alternative to triosephosphate isomerase for metabolizing
MGS is a small protein of about 13 to 17 kDa. An aspartate residue is involved
in the catalytic mechanism. Methylglyoxal synthase contains a domain shared by other enzymes. Other proteins containing this domain include purine biosynthesis protein PurH and carbamoyl phosphate synthetase.
This entry represents a short conserved region that contains an aspartate residue involved in catalytic activty.
GO:0019242 methylglyoxal biosynthetic process
GO:0008929 methylglyoxal synthase activity
No terms assigned in this category.