WWE domain, subgroup (IPR018123)

Short name: WWE-dom_subgr

Overlapping homologous superfamilies

Domain relationships

  • WWE domain (IPR004170)
    • WWE domain, subgroup (IPR018123)


The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP ribose conjugation systems. This domain is found as a tandem repeat at the N-terminal of Deltex, a cytosolic effector of Notch signalling thought to bind the N-terminal of the Notch receptor [PMID: 16271883]. It is also found as an interaction module in protein ubiquination and ADP ribosylation proteins [PMID: 11343911].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.