PTM

Surfactant-associated polypeptide, palmitoylation site (IPR018051)

Short name: SP-C_palmitoylation_site

Description

Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-C, a component of surfactant, is a highly hydrophobic peptide of 35 amino acid residues which is processed from a larger precursor protein. SP-C is post-translationally modified by the covalent attachment of two palmitoyl groups on two adjacent cysteines [PMID: 2326260]. The exception is canine SP-C, in which the second Cys is replaced by Phe [PMID: 2015882].

GO terms

Biological Process

GO:0007585 respiratory gaseous exchange

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns